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Expanding the Number of “Druggable” Targets: Non-Enzymes and Protein-Protein Interactions

Following sequencing and assembly of the human genome, the preferred methods for identification of new drug targets have changed dramatically. Modern tactics such as genome-wide association studies (GWAS) and deep sequencing are fundamentally different from the pharmacology-guided approaches used pr...

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Main Authors: Makley, Leah N., Gestwicki, Jason E.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531880/
https://ncbi.nlm.nih.gov/pubmed/23253128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12066
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