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Essential multimeric enzymes in kinetoplastid parasites: A host of potentially druggable protein-protein interactions

Parasitic diseases caused by kinetoplastid parasites of the genera Trypanosoma and Leishmania are an urgent public health crisis in the developing world. These closely related species possess a number of multimeric enzymes in highly conserved pathways involved in vital functions, such as redox homeo...

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Publicat a:PLoS Negl Trop Dis
Autors principals: Wachsmuth, Leah M., Johnson, Meredith G., Gavenonis, Jason
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507555/
https://ncbi.nlm.nih.gov/pubmed/28662026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005720
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