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Chemogenetic characterization of inositol phosphate metabolic pathway reveals druggable enzymes for targeting kinetoplastid parasites
Kinetoplastids cause Chagas disease, Human African Trypanosomiasis (HAT) and leishmaniases. Current treatments for these diseases are toxic and inefficient, and our limited knowledge of drug targets and inhibitors has dramatically hindered the development of new drugs. Here we used a chemogenetic ap...
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| Veröffentlicht in: | Cell Chem Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4876820/ https://ncbi.nlm.nih.gov/pubmed/27133314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2016.03.015 |
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