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Inositol phosphate pathway controls transcription of telomeric expression sites in trypanosomes

African trypanosomes evade clearance by host antibodies by periodically changing their variant surface glycoprotein (VSG) coat. They transcribe only one VSG gene at a time from 1 of about 20 telomeric expression sites (ESs). They undergo antigenic variation by switching transcription between telomer...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Cestari, Igor, Stuart, Ken
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450425/
https://ncbi.nlm.nih.gov/pubmed/25964327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501206112
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