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Inositol phosphate pathway controls transcription of telomeric expression sites in trypanosomes

African trypanosomes evade clearance by host antibodies by periodically changing their variant surface glycoprotein (VSG) coat. They transcribe only one VSG gene at a time from 1 of about 20 telomeric expression sites (ESs). They undergo antigenic variation by switching transcription between telomer...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Cestari, Igor, Stuart, Ken
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450425/
https://ncbi.nlm.nih.gov/pubmed/25964327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501206112
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