Host–rabies virus protein–protein interactions as druggable antiviral targets

We present an unconventional approach to antiviral drug discovery, which is used to identify potent small molecules against rabies virus. First, we conceptualized viral capsid assembly as occurring via a host-catalyzed biochemical pathway, in contrast to the classical view of capsid formation by sel...

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Detalhes bibliográficos
Main Authors: Lingappa, Usha F., Wu, Xianfu, Macieik, Amanda, Yu, Shao Feng, Atuegbu, Andy, Corpuz, Michael, Francis, Jean, Nichols, Christine, Calayag, Alfredo, Shi, Hong, Ellison, James A., Harrell, Emma K. T., Asundi, Vinod, Lingappa, Jaisri R., Prasad, M. Dharma, Lipkin, W. Ian, Dey, Debendranath, Hurt, Clarence R., Lingappa, Vishwanath R., Hansen, William J., Rupprecht, Charles E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593902/
https://ncbi.nlm.nih.gov/pubmed/23404707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210198110
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