Host–rabies virus protein–protein interactions as druggable antiviral targets

We present an unconventional approach to antiviral drug discovery, which is used to identify potent small molecules against rabies virus. First, we conceptualized viral capsid assembly as occurring via a host-catalyzed biochemical pathway, in contrast to the classical view of capsid formation by sel...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Lingappa, Usha F., Wu, Xianfu, Macieik, Amanda, Yu, Shao Feng, Atuegbu, Andy, Corpuz, Michael, Francis, Jean, Nichols, Christine, Calayag, Alfredo, Shi, Hong, Ellison, James A., Harrell, Emma K. T., Asundi, Vinod, Lingappa, Jaisri R., Prasad, M. Dharma, Lipkin, W. Ian, Dey, Debendranath, Hurt, Clarence R., Lingappa, Vishwanath R., Hansen, William J., Rupprecht, Charles E.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2013
Θέματα:
PNAS Plus
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3593902/
https://ncbi.nlm.nih.gov/pubmed/23404707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210198110
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