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A Model-Based Clustering Method for Genomic Structural Variant Prediction and Genotyping Using Paired-End Sequencing Data

Structural variation (SV) has been reported to be associated with numerous diseases such as cancer. With the advent of next generation sequencing (NGS) technologies, various types of SV can be potentially identified. We propose a model based clustering approach utilizing a set of features defined fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hayes, Matthew, Pyon, Yoon Soo, Li, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531386/
https://ncbi.nlm.nih.gov/pubmed/23300804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052881
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