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A Model-Based Clustering Method for Genomic Structural Variant Prediction and Genotyping Using Paired-End Sequencing Data

Structural variation (SV) has been reported to be associated with numerous diseases such as cancer. With the advent of next generation sequencing (NGS) technologies, various types of SV can be potentially identified. We propose a model based clustering approach utilizing a set of features defined fo...

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Detalles Bibliográficos
Main Authors: Hayes, Matthew, Pyon, Yoon Soo, Li, Jing
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531386/
https://ncbi.nlm.nih.gov/pubmed/23300804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052881
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