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A Model-Based Clustering Method for Genomic Structural Variant Prediction and Genotyping Using Paired-End Sequencing Data

Structural variation (SV) has been reported to be associated with numerous diseases such as cancer. With the advent of next generation sequencing (NGS) technologies, various types of SV can be potentially identified. We propose a model based clustering approach utilizing a set of features defined fo...

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Détails bibliographiques
Auteurs principaux: Hayes, Matthew, Pyon, Yoon Soo, Li, Jing
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531386/
https://ncbi.nlm.nih.gov/pubmed/23300804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052881
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