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A Streamlined Method for Detecting Structural Variants in Cancer Genomes by Short Read Paired-End Sequencing
Defining the architecture of a specific cancer genome, including its structural variants, is essential for understanding tumor biology, mechanisms of oncogenesis, and for designing effective personalized therapies. Short read paired-end sequencing is currently the most sensitive method for detecting...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483208/ https://ncbi.nlm.nih.gov/pubmed/23144753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048314 |
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