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Accurate indel prediction using paired-end short reads

BACKGROUND: One of the major open challenges in next generation sequencing (NGS) is the accurate identification of structural variants such as insertions and deletions (indels). Current methods for indel calling assign scores to different types of evidence or counter-evidence for the presence of an...

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Detalhes bibliográficos
Main Authors: Grimm, Dominik, Hagmann, Jörg, Koenig, Daniel, Weigel, Detlef, Borgwardt, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614465/
https://ncbi.nlm.nih.gov/pubmed/23442375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-132
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