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Accurate indel prediction using paired-end short reads

BACKGROUND: One of the major open challenges in next generation sequencing (NGS) is the accurate identification of structural variants such as insertions and deletions (indels). Current methods for indel calling assign scores to different types of evidence or counter-evidence for the presence of an...

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Bibliografske podrobnosti
Main Authors: Grimm, Dominik, Hagmann, Jörg, Koenig, Daniel, Weigel, Detlef, Borgwardt, Karsten
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614465/
https://ncbi.nlm.nih.gov/pubmed/23442375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-132
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