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Accurate indel prediction using paired-end short reads

BACKGROUND: One of the major open challenges in next generation sequencing (NGS) is the accurate identification of structural variants such as insertions and deletions (indels). Current methods for indel calling assign scores to different types of evidence or counter-evidence for the presence of an...

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Détails bibliographiques
Auteurs principaux: Grimm, Dominik, Hagmann, Jörg, Koenig, Daniel, Weigel, Detlef, Borgwardt, Karsten
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614465/
https://ncbi.nlm.nih.gov/pubmed/23442375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-132
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