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Inferring short tandem repeat variation from paired-end short reads
The advances of high-throughput sequencing offer an unprecedented opportunity to study genetic variation. This is challenged by the difficulty of resolving variant calls in repetitive DNA regions. We present a Bayesian method to estimate repeat-length variation from paired-end sequence read data. Th...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919575/ https://ncbi.nlm.nih.gov/pubmed/24353318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1313 |
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