Inferring short tandem repeat variation from paired-end short reads

The advances of high-throughput sequencing offer an unprecedented opportunity to study genetic variation. This is challenged by the difficulty of resolving variant calls in repetitive DNA regions. We present a Bayesian method to estimate repeat-length variation from paired-end sequence read data. Th...

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Bibliografske podrobnosti
Main Authors: Cao, Minh Duc, Tasker, Edward, Willadsen, Kai, Imelfort, Michael, Vishwanathan, Sailaja, Sureshkumar, Sridevi, Balasubramanian, Sureshkumar, Bodén, Mikael
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Methods Online
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919575/
https://ncbi.nlm.nih.gov/pubmed/24353318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1313
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