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Rare variant discovery and calling by sequencing pooled samples with overlaps
Motivation: For many complex traits/diseases, it is believed that rare variants account for some of the missing heritability that cannot be explained by common variants. Sequencing a large number of samples through DNA pooling is a cost-effective strategy to discover rare variants and to investigate...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530907/ https://ncbi.nlm.nih.gov/pubmed/23104896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts645 |
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