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Quantitative group testing-based overlapping pool sequencing to identify rare variant carriers
BACKGROUND: Genome-wide association studies have revealed that rare variants are responsible for a large portion of the heritability of some complex human diseases. This highlights the increasing importance of detecting and screening for rare variants. Although the massively parallel sequencing tech...
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| Udgivet i: | BMC Bioinformatics |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229885/ https://ncbi.nlm.nih.gov/pubmed/24934981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-195 |
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