Nalaganje...

Crystal Structure of the HLA-DM - HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

HLA-DR molecules bind microbial peptides in an endosomal compartment and present them on the cell surface for CD4 T cell surveillance. HLA-DM plays a critical role in the endosomal peptide selection process. The structure of the HLA-DM – HLA-DR complex shows major rearrangements of the HLA-DR peptid...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Pos, Wouter, Sethi, Dhruv K., Call, Melissa J., Schulze, Monika-Sarah E. D., Anders, Anne-Kathrin, Pyrdol, Jason, Wucherpfennig, Kai W.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530167/
https://ncbi.nlm.nih.gov/pubmed/23260142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.025
Oznake: Označite
Brez oznak, prvi označite!