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HLA-DM Captures Partially Empty HLA-DR Molecules for Catalyzed Peptide Removal

The mechanisms of HLA-DM catalyzed peptide exchange remain uncertain. We found that all stages of the interaction of DM with HLA-DR were dependent on the occupancy state of the peptide binding groove. High-affinity peptides were protected from removal by DM through two mechanisms: peptide binding in...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Anders, Anne-Kathrin, Call, Melissa J., Schulze, Monika-Sarah E. D., Fowler, Kevin D., Schubert, David A., Seth, Nilufer P., Sundberg, Eric J., Wucherpfennig, Kai W.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018327/
https://ncbi.nlm.nih.gov/pubmed/21131964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1967
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