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β-Adrenergic stimulation increases the intra-sarcoplasmic reticulum Ca(2+) threshold for Ca(2+) wave generation
β-Adrenergic signalling induces positive inotropic effects on the heart that associate with pro-arrhythmic spontaneous Ca(2+) waves. A threshold level of sarcoplasmic reticulum (SR) Ca(2+) ([Ca(2+)](SR)) is necessary to trigger Ca(2+) waves, and whether the increased incidence of Ca(2+) waves during...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3530119/ https://ncbi.nlm.nih.gov/pubmed/22988136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.236117 |
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