Alteration of sarcoplasmic reticulum Ca(2+) release termination by ryanodine receptor sensitization and in heart failure

Many physiological processes and pharmacological agents modulate the ryanodine receptor (RyR), the primary sarcoplasmic reticulum (SR) Ca(2+) release channel in the heart. However, how such modulations translate into functional effects during cardiac excitation–contraction coupling (ECC) is much les...

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Detalhes bibliográficos
Main Authors: Domeier, Timothy L, Blatter, Lothar A, Zima, Aleksey V
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790258/
https://ncbi.nlm.nih.gov/pubmed/19736296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.177576
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