β-Adrenergic stimulation increases the intra-sarcoplasmic reticulum Ca(2+) threshold for Ca(2+) wave generation

β-Adrenergic signalling induces positive inotropic effects on the heart that associate with pro-arrhythmic spontaneous Ca(2+) waves. A threshold level of sarcoplasmic reticulum (SR) Ca(2+) ([Ca(2+)](SR)) is necessary to trigger Ca(2+) waves, and whether the increased incidence of Ca(2+) waves during...

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Bibliografiset tiedot
Päätekijät: Domeier, Timothy L, Maxwell, Joshua T, Blatter, Lothar A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2012
Aiheet:
Cardiovascular
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530119/
https://ncbi.nlm.nih.gov/pubmed/22988136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.236117
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