Facilitation of cytosolic calcium wave propagation by local calcium uptake into the sarcoplasmic reticulum in cardiac myocytes

The widely accepted paradigm for cytosolic Ca(2+) wave propagation postulates a ‘fire-diffuse-fire’ mechanism where local Ca(2+)-induced Ca(2+) release (CICR) from the sarcoplasmic reticulum (SR) via ryanodine receptor (RyR) Ca(2+) release channels diffuses towards and activates neighbouring release...

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Autores principales: Maxwell, Joshua T, Blatter, Lothar A
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2012
Materias:
Cardiovascular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530115/
https://ncbi.nlm.nih.gov/pubmed/22988145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.239434
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