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Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate
Recent studies have identified a number of transcriptional regulators, including E2A, early B-cell factor 1 (EBF1), FOXO1, and paired box gene 5 (PAX5), that promote early B-cell development. However, how this ensemble of regulators mechanistically promotes B-cell fate remains poorly understood. Her...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529039/ https://ncbi.nlm.nih.gov/pubmed/23213261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211427109 |
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