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The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor

Recent studies have identified a number of transcriptional regulators, including E proteins, EBF1, FOXO1, and PAX5, that act together to orchestrate the B-cell fate. However, it still remains unclear as to how they are linked at the earliest stages of B-cell development. Here, we show that lymphocyt...

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Bibliografische gegevens
Hoofdauteurs: Welinder, Eva, Mansson, Robert, Mercer, Elinore M., Bryder, David, Sigvardsson, Mikael, Murre, Cornelis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198373/
https://ncbi.nlm.nih.gov/pubmed/21972416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111766108
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