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E2A proteins promote development of lymphoid-primed multipotent progenitors

The first lymphoid restricted progeny of HSCs are lymphoid-primed multipotent progenitors (LMPPs), which have little erythro-myeloid potential but retain lymphoid and granulocyte/macrophage differentiation capacity. Despite recent advances in the identification of LMPPs the transcription factors ess...

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Détails bibliographiques
Auteurs principaux: Dias, Sheila, Månsson, Robert, Gurbuxani, Sandeep, Sigvardsson, Mikael, Kee, Barbara L.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2600583/
https://ncbi.nlm.nih.gov/pubmed/18674933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.05.015
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