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Ezh2 represses transcription of innate lymphoid genes in B lymphocyte progenitors and maintains the B-2 cell fate

Lymphocyte lineage specification and commitment requires the activation of lineage specific genes and repression of alternative lineage genes respectively. The mechanisms governing alternative lineage gene repression and commitment in lymphocytes are largely unknown. Here, we demonstrate that Ezh2,...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Jacobsen, Jennifer A., Bartom, Elizabeth T., Sigvardsson, Mikael, Kee, Barbara L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7344269/
https://ncbi.nlm.nih.gov/pubmed/32094206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901188
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