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Zbtb1 prevents default myeloid differentiation of lymphoid-primed multipotent progenitors

Zbtb1 is a transcription factor that prevents DNA damage and p53-mediated apoptosis in replicating immune progenitors, affecting lymphoid as well as myeloid development when hematopoietic progenitors are in competition in mixed bone marrow chimeras. However, Zbtb1-deficient mice do not have an appar...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Xianyu, Lu, Ying, Cao, Xin, Zhen, Tao, Kovalovsky, Damian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312274/
https://ncbi.nlm.nih.gov/pubmed/27542215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11356
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