Zbtb1 controls NKp46(+) ROR-gamma-T(+) innate lymphoid cell (ILC3) development

Innate lymphoid cells (ILCs) play a central role conferring protection at the mucosal frontier. In this study, we have identified a requirement of the transcription factor Zbtb1 for the development of RORγt(+) ILCs (ILC3s). Zbtb1-deficient mice lacked NKp46(+) ILC3 cells in the lamina propria of the...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lu, Ying, Zhang, Xianyu, Bouladoux, Nicolas, Kaul, Saransh Neel, Jin, Kangxin, Sant’Angelo, Derek, Belkaid, Yasmine, Kovalovsky, Damian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Priority Research Paper: Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593530/
https://ncbi.nlm.nih.gov/pubmed/28915559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19645
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