A truncated peptide from p35, a Cdk5 activator, prevents Alzheimer's disease phenotypes in model mice

Alzheimer's disease (AD), one of the leading neurodegenerative disorders of older adults, which causes major socioeconomic burdens globally, lacks effective therapeutics without significant side effects. Besides the hallmark pathology of amyloid plaques and neurofibrillary tangles (NFTs), it ha...

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Bibliografische gegevens
Hoofdauteurs: Shukla, Varsha, Zheng, Ya-Li, Mishra, Santosh K., Amin, Niranjana D., Steiner, Joseph, Grant, Philip, Kesavapany, Sashi, Pant, Harish C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Federation of American Societies for Experimental Biology 2013
Onderwerpen:
Research Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528323/
https://ncbi.nlm.nih.gov/pubmed/23038754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-217497
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