A truncated peptide from p35, a Cdk5 activator, prevents Alzheimer's disease phenotypes in model mice

Alzheimer's disease (AD), one of the leading neurodegenerative disorders of older adults, which causes major socioeconomic burdens globally, lacks effective therapeutics without significant side effects. Besides the hallmark pathology of amyloid plaques and neurofibrillary tangles (NFTs), it ha...

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Main Authors: Shukla, Varsha, Zheng, Ya-Li, Mishra, Santosh K., Amin, Niranjana D., Steiner, Joseph, Grant, Philip, Kesavapany, Sashi, Pant, Harish C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Federation of American Societies for Experimental Biology 2013
Ábhair:
Research Communications
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528323/
https://ncbi.nlm.nih.gov/pubmed/23038754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-217497
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