Comparison of the Binding and Functional Properties of Two Structurally Different D2 Dopamine Receptor Subtype Selective Compounds

[Image: see text] We previously reported on the synthesis of substituted phenyl-4-hydroxy-1-piperidyl indole analogues with nanomolar affinity at D2 dopamine receptors, ranging from 10- to 100-fold selective for D2 compared to the D3 dopamine receptor subtype. More recently, we evaluated a panel of...

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Main Authors: Luedtke, Robert R., Mishra, Yogesh, Wang, Qi, Griffin, Suzy A., Bell-Horner, Cathy, Taylor, Michelle, Vangveravong, Suwanna, Dillon, Glenn H., Huang, Ren-Qi, Reichert, David E., Mach, Robert H.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2012
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526968/
https://ncbi.nlm.nih.gov/pubmed/23259040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn300142q
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