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Synthesis and characterization of selective dopamine D(2) receptor ligands using aripiprazole as the lead compound
A series of compounds structurally related to aripiprazole (1), an atypical antipsychotic and antidepressant used clinically for the treatment of schizophrenia, bipolar disorder, and depression, have been prepared and evaluated for affinity at D(2-like) dopamine receptors. These compounds also share...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3118479/ https://ncbi.nlm.nih.gov/pubmed/21536445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.04.021 |
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