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Synthesis and characterization of selective dopamine D(2) receptor ligands using aripiprazole as the lead compound

A series of compounds structurally related to aripiprazole (1), an atypical antipsychotic and antidepressant used clinically for the treatment of schizophrenia, bipolar disorder, and depression, have been prepared and evaluated for affinity at D(2-like) dopamine receptors. These compounds also share...

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Autores principales: Vangveravong, Suwanna, Zhang, Zhanbin, Taylor, Michelle, Bearden, Melissa, Xu, Jinbin, Cui, Jinquan, Wang, Wei, Luedtke, Robert R., Mach, Robert H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118479/
https://ncbi.nlm.nih.gov/pubmed/21536445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.04.021
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