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Evaluation of D2 and D3 Dopamine Receptor Selective Compounds on L-Dopa Dependent Abnormal Involuntary Movements in Rats

A panel of novel D2 and D3 dopamine receptor selective antagonists, partial agonists and full agonists have been evaluated for the ability to attenuate L-dopa associated abnormal involuntary movements (AIMs) in 6-hydroxydopamine (6-OHDA) unilaterally lesioned male Sprague Dawley rats, which is an an...

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Detalhes bibliográficos
Main Authors: Kumar, Rakesh, Riddle, Lindsay R., Griffin, Suzy A., Chu, Wenjua, Vangveravong, Suwanna, Neisewander, Janet, Mach, Robert H., Luedtke, Robert R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106465/
https://ncbi.nlm.nih.gov/pubmed/19371586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.01.019
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