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Evaluation of the D3 Dopamine Receptor Selective Antagonist PG01037 on L-Dopa Dependent Abnormal Involuntary Movements in Rats
The D3 dopamine receptor selective antagonist PG01037 has been evaluated for the ability to attenuate L-dopa associated abnormal involuntary movements (AIMs) in unilaterally lesioned male Sprague Dawley rats, which is a model of L-dopa-dependent dyskinesia in patients with Parkinson’s Disease. The i...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820009/ https://ncbi.nlm.nih.gov/pubmed/19371585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2009.01.020 |
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