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Defining the functional footprint for recognition and repair of deaminated DNA
Spontaneous deamination of DNA is mutagenic, if it is not repaired by the base excision repair (BER) pathway. Crystallographic data suggest that each BER enzyme has a compact DNA binding site. However, these structures lack information about poorly ordered termini, and the energetic contributions of...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3526306/ https://ncbi.nlm.nih.gov/pubmed/23074184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks952 |
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