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Nonspecific DNA Binding and Coordination of the First Two Steps of Base Excision Repair

The base excision repair (BER) pathway repairs a wide variety of damaged nucleobases in DNA. This pathway is initiated by a DNA repair glycosylase, which locates the site of damage and catalyzes the excision of the damaged nucleobase. The resulting abasic site is further processed by apurinic/apyrim...

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Detalhes bibliográficos
Main Authors: Baldwin, Michael R., O'Brien, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935503/
https://ncbi.nlm.nih.gov/pubmed/20701268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100889r
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