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DNA charge transport as a first step in coordinating the detection of lesions by repair proteins

Damaged bases in DNA are known to lead to errors in replication and transcription, compromising the integrity of the genome. We have proposed a model where repair proteins containing redox-active [4Fe-4S] clusters utilize DNA charge transport (CT) as a first step in finding lesions. In this model, t...

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Detalhes bibliográficos
Main Authors: Sontz, Pamela A., Mui, Timothy P., Fuss, Jill O., Tainer, John A., Barton, Jacqueline K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277573/
https://ncbi.nlm.nih.gov/pubmed/22308447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120063109
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