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DNA charge transport as a first step in coordinating the detection of lesions by repair proteins

Damaged bases in DNA are known to lead to errors in replication and transcription, compromising the integrity of the genome. We have proposed a model where repair proteins containing redox-active [4Fe-4S] clusters utilize DNA charge transport (CT) as a first step in finding lesions. In this model, t...

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Bibliografiska uppgifter
Huvudupphovsmän: Sontz, Pamela A., Mui, Timothy P., Fuss, Jill O., Tainer, John A., Barton, Jacqueline K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277573/
https://ncbi.nlm.nih.gov/pubmed/22308447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120063109
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