Redox signaling between DNA repair proteins for efficient lesion detection

Base excision repair (BER) enzymes maintain the integrity of the genome, and in humans, BER mutations are associated with cancer. Given the remarkable sensitivity of DNA-mediated charge transport (CT) to mismatched and damaged base pairs, we have proposed that DNA repair glycosylases (EndoIII and Mu...

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Main Authors: Boal, Amie K., Genereux, Joseph C., Sontz, Pamela A., Gralnick, Jeffrey A., Newman, Dianne K., Barton, Jacqueline K.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2009
主題:
Physical Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741234/
https://ncbi.nlm.nih.gov/pubmed/19720997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908059106
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