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Protein–DNA charge transport: Redox activation of a DNA repair protein by guanine radical
DNA charge transport (CT) chemistry provides a route to carry out oxidative DNA damage from a distance in a reaction that is sensitive to DNA mismatches and lesions. Here, DNA-mediated CT also leads to oxidation of a DNA-bound base excision repair enzyme, MutY. DNA-bound Ru(III), generated through a...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC553321/ https://ncbi.nlm.nih.gov/pubmed/15738421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409410102 |
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