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Human AP Endonuclease I Stimulates Multiple-Turnover Base Excision by Alkyladenine DNA Glycosylase

Human alkyladenine DNA glycosylase (AAG) locates and excises a wide variety of damaged purine bases from DNA, including hypoxanthine that is formed by the oxidative deamination of adenine. We used steady state, pre-steady state, and single-turnover kinetic assays to show that the multiple-turnover e...

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Sonraí Bibleagrafaíochta
Main Authors: Baldwin, Michael R., O’Brien, Patrick J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762795/
https://ncbi.nlm.nih.gov/pubmed/19449863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900517y
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