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Efficient Recognition of an Unpaired Lesion by a DNA Repair Glycosylase

The duplex structure of DNA, with its internal base pairing, protects the nucleobases from chemical damage, but it also poses a barrier to DNA modifying enzymes, including the enzymes that recognize and repair DNA damage. It is known that unpaired, or bulged nucleotides are significantly more access...

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Detalhes bibliográficos
Main Authors: Lyons, Derek M., O’Brien, Patrick J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797315/
https://ncbi.nlm.nih.gov/pubmed/19924854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja908378y
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