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C911: A Bench-Level Control for Sequence Specific siRNA Off-Target Effects

Small interfering RNAs (siRNAs) have become a ubiquitous experimental tool for down-regulating mRNAs. Unfortunately, off-target effects are a significant source of false positives in siRNA experiments and an effective control for them has not previously been identified. We introduce two methods of m...

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Detaylı Bibliyografya
Asıl Yazarlar: Buehler, Eugen, Chen, Yu-Chi, Martin, Scott
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522603/
https://ncbi.nlm.nih.gov/pubmed/23251657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051942
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