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siRNA Specificity: RNAi Mechanisms and Strategies to Reduce Off-Target Effects
Short interfering RNAs (siRNAs) are processed from long double-stranded RNA (dsRNA), and a guide strand is selected and incorporated into the RNA-induced silencing complex (RISC). Within RISC, a member of the Argonaute protein family directly binds the guide strand and the siRNA guides RISC to fully...
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| Publicado en: | Front Plant Sci |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7876455/ https://ncbi.nlm.nih.gov/pubmed/33584737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2020.526455 |
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