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siRNA Specificity: RNAi Mechanisms and Strategies to Reduce Off-Target Effects
Short interfering RNAs (siRNAs) are processed from long double-stranded RNA (dsRNA), and a guide strand is selected and incorporated into the RNA-induced silencing complex (RISC). Within RISC, a member of the Argonaute protein family directly binds the guide strand and the siRNA guides RISC to fully...
Tallennettuna:
| Julkaisussa: | Front Plant Sci |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Frontiers Media S.A.
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7876455/ https://ncbi.nlm.nih.gov/pubmed/33584737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2020.526455 |
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