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siPools: highly complex but accurately defined siRNA pools eliminate off-target effects
Short interfering RNAs (siRNAs) are widely used as tool for gene inactivation in basic research and therapeutic applications. One of the major shortcomings of siRNA experiments are sequence-specific off-target effects. Such effects are largely unpredictable because siRNAs can affect partially comple...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4081087/ https://ncbi.nlm.nih.gov/pubmed/24875475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku480 |
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