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C911: A Bench-Level Control for Sequence Specific siRNA Off-Target Effects
Small interfering RNAs (siRNAs) have become a ubiquitous experimental tool for down-regulating mRNAs. Unfortunately, off-target effects are a significant source of false positives in siRNA experiments and an effective control for them has not previously been identified. We introduce two methods of m...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3522603/ https://ncbi.nlm.nih.gov/pubmed/23251657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051942 |
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