Genome Editing of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells With Zinc Finger Nuclease for Cellular Imaging

RATIONALE: Molecular imaging has proven to be a vital tool in the characterization of stem cell behavior in vivo. However, the integration of reporter genes has typically relied upon random integration, a method that is associated with unwanted insertional mutagenesis and position effects on transge...

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Main Authors: Wang, Yongming, Zhang, Wendy Y., Hu, Shijun, Lan, Feng, Lee, Andrew S., Huber, Bruno, Lisowski, Leszek, Liang, Ping, Huang, Mei, de Almeida, Patricia E., Won, Jong H., Sun, Ning, Robbins, Robert C., Kay, Mark A., Urnov, Fyodor D., Wu, Joseph C.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518748/
https://ncbi.nlm.nih.gov/pubmed/22967807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.274969
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