Genome Editing of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells With Zinc Finger Nuclease for Cellular Imaging

RATIONALE: Molecular imaging has proven to be a vital tool in the characterization of stem cell behavior in vivo. However, the integration of reporter genes has typically relied upon random integration, a method that is associated with unwanted insertional mutagenesis and position effects on transge...

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Autori principali: Wang, Yongming, Zhang, Wendy Y., Hu, Shijun, Lan, Feng, Lee, Andrew S., Huber, Bruno, Lisowski, Leszek, Liang, Ping, Huang, Mei, de Almeida, Patricia E., Won, Jong H., Sun, Ning, Robbins, Robert C., Kay, Mark A., Urnov, Fyodor D., Wu, Joseph C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518748/
https://ncbi.nlm.nih.gov/pubmed/22967807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.274969
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