Gene Editing of Human Embryonic Stem Cells via an Engineered Baculoviral Vector Carrying Zinc-finger Nucleases

Human embryonic stem (hES) cells are renewable cell sources that have potential applications in regenerative medicine. The development of technologies to produce permanent and site-specific genome modifications is in demand to achieve future medical implementation of hES cells. We report herein that...

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Detalhes bibliográficos
Main Authors: Lei, Yuning, Lee, Chi-Lin, Joo, Kye-Il, Zarzar, Jonathan, Liu, Yarong, Dai, Bingbing, Fox, Victoria, Wang, Pin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098635/
https://ncbi.nlm.nih.gov/pubmed/21326219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.12
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