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Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

Broad applications of zinc finger nuclease (ZFN) technology—which allows targeted genome editing—in research, medicine, and biotechnology are hampered by the lack of a convenient, rapid, and publicly available method for the synthesis of functional ZFNs. Here we describe an efficient and easy-to-pra...

詳細記述

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書誌詳細
主要な著者: Kim, Hye Joo, Lee, Hyung Joo, Kim, Hyojin, Cho, Seung Woo, Kim, Jin-Soo
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704428/
https://ncbi.nlm.nih.gov/pubmed/19470664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.089417.108
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