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Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly
Broad applications of zinc finger nuclease (ZFN) technology—which allows targeted genome editing—in research, medicine, and biotechnology are hampered by the lack of a convenient, rapid, and publicly available method for the synthesis of functional ZFNs. Here we describe an efficient and easy-to-pra...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704428/ https://ncbi.nlm.nih.gov/pubmed/19470664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.089417.108 |
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